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Palm reading to diagnose Atopic Dermatitis?
Blog January 19, 2025

Palm reading to diagnose Atopic Dermatitis?

Dr. Yeonseung Choe
Dr. Yeonseung Choe
Chief Director

Filaggrin plays an important role in the skin barrier. For more detailed information on filaggrin, you can refer to our previous posts:

It's important to note that even among individuals with atopy, clinical and biophysical characteristics can differ depending on specific atopy gene mutations. Specifically, in cases with a filaggrin gene mutation, atopy can be understood as presenting a more severe phenotype. You can find a blog post summarizing the detailed content here.

Palmar Hyperlinearity

An interesting point is *palmar hyperlinearity*. The pattern of palm creases can vary depending on the filaggrin gene. Related research includes:

Fukuie, T., Yasuoka, R., Fujiyama, T., Sakabe, J., Taguchi, T., & Tokura, Y. (2019). Palmar hyperlinearity in early childhood atopic dermatitis is associated with filaggrin mutation and sensitization to egg. Pediatric Dermatology. doi:10.1111/pde.13752

The pattern of palm creases can be indicative of the following:

  • How visible the palm lines are
  • The depth of the palm lines
  • The number of creases on the palm
  • The presence or absence of palm lines crossing the thenar eminence

Research indicates that these palm line patterns may be a sign of filaggrin gene mutations, and findings show statistical significance. It may also be interesting to read more resources.

Summary

  1. Take a look at your palm lines.

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Dr. Yeonseung Choe

Dr. Yeonseung Choe Chief Director

I have met many patients who came after visiting multiple medical institutions and departments for persistent or recurrent conditions. Symptoms normally handled by different specialties—such as abdominal pain, headaches, palpitations, dizziness, and insomnia—may overlap in one person. Sometimes there is no clear improvement despite taking medication for each symptom, and being unwell gradually becomes part of daily life. In these cases, I look beyond individual diagnoses and examine how the symptoms connect and change together. Asking only about the most uncomfortable symptom today does not reveal the full course. I look at when the body first began to change and what happened after illness, surgery, childbirth, or starting and stopping medication. I also review changes in weight, diet, and sleep, then trace which symptoms improved with previous treatment and which remained. Test results, diagnoses, and the course of previous treatment are important for understanding the current condition. Clinical research in modern Korean medicine, physiological and pathological research in modern medicine, and observations recorded in classical Korean medicine texts offer different perspectives on the same body. Rather than fitting a patient into one perspective, I consider what each can and cannot explain and look for clues that connect symptoms and treatment histories that were previously considered separately.

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