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Atopic Dermatitis and Warts: Immune Imbalance, the Two-Faced Culprit | Incheon Warts
Blog August 27, 2025

Atopic Dermatitis and Warts: Immune Imbalance, the Two-Faced Culprit | Incheon Warts

Dr. Yeonseung Choe
Dr. Yeonseung Choe
Chief Director

This is the story of Ms. B, a woman in her 30s. She says she has suffered from atopic dermatitis since childhood, and recently her condition has worsened, particularly around her neck and lower back. Unable to resist the itch, she would scratch, leading to oozing, and her skin became even drier, trapping her in a cycle of inflammation. Simultaneously, warts, which she had experienced once or twice on her soles in the past, recurred this time on the outer groin area. She received cryotherapy once, but felt despair when she saw them slowly growing back in size after two weeks.

The Link Between Two Skin Conditions

Why was she suffering from two separate skin conditions simultaneously? While warts are infectious diseases caused by a virus (HPV), atopic dermatitis is known as a chronic inflammatory disease resulting from a combination of impaired skin barrier function and hypersensitivity of the immune response. Although the underlying causes of the two diseases seem different, there is a hidden link that goes beyond conventional wisdom.

If Ms. B's skin problems were merely due to localized inflammation, they should have responded sufficiently to topical treatments such as over-the-counter ointments (steroid ointments) or cryotherapy. However, in her case, over-the-counter ointments only temporarily suppressed the itching without providing a fundamental solution, and she experienced wart recurrence after removal. This is our second clue, indicating that we need to investigate the limitations of existing treatments and find the true underlying cause.

Instability of the Immune System

Our skin serves as the primary defense line against external viruses and bacteria, while also acting as a mirror that constantly reflects our body's internal state. Frequent wart recurrence and chronic atopic oozing can both be signs of an unstable immune system. Atopic patients have weakened skin barrier function, leading to skin barrier damage, making them more vulnerable to viral infiltration than healthy individuals.

This complex situation is like a malfunctioning fire alarm. Even though the actual spark is very small, the entire system overreacts, sounding loud sirens throughout the building, exhausting everyone. This is due to immune imbalance that can be triggered by chronic stress, late sleep, and unhealthy lifestyle habits.

Cause of Warts: Human Papillomavirus (HPV)

The virus that is the direct cause of warts. Not everyone infected with the HPV virus develops warts; the virus proliferates and forms warts when immunity is weakened. Research also supports this, showing that atopic patients have a 1.105 times higher risk of viral wart infection and more than 5 times higher risk of molluscum contagiosum infection compared to healthy individuals. This is because atopic dermatitis causes abnormalities in skin function or systemic immune function.

What is the Solution?

So, what is the solution? Picking at warts or scratching atopic areas are merely temporary fixes. Beyond 'temporarily eliminating symptoms,' the focus should be on 'creating an environment where viruses cannot thrive.'

Key

The key is not just to solve surface skin problems, but to correct internal imbalances and strengthen immune function.

Key Takeaways

  • Atopic dermatitis and warts may share a common underlying cause: 'immune imbalance.'
  • If topical treatments are insufficient, systemic immunity management through lifestyle improvements is necessary.
  • An integrated approach to managing atopic dermatitis and warts is effective.

If skin problems recur despite relying solely on topical treatments, without a clear cause identified through examination, it's necessary to consider the possibility that the root of the problem lies in the systemic immune state. This is not medical advice for a specific individual. However, it can serve as an important clue for understanding a key pattern in how our bodies react to the external environment.

If you, too, have been suffering from chronic skin problems for a long time, it's time to comprehensively review your immune status, not just the visible symptoms.

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Dr. Yeonseung Choe

Dr. Yeonseung Choe Chief Director

I have met many patients who came after visiting multiple medical institutions and departments for persistent or recurrent conditions. Symptoms normally handled by different specialties—such as abdominal pain, headaches, palpitations, dizziness, and insomnia—may overlap in one person. Sometimes there is no clear improvement despite taking medication for each symptom, and being unwell gradually becomes part of daily life. In these cases, I look beyond individual diagnoses and examine how the symptoms connect and change together. Asking only about the most uncomfortable symptom today does not reveal the full course. I look at when the body first began to change and what happened after illness, surgery, childbirth, or starting and stopping medication. I also review changes in weight, diet, and sleep, then trace which symptoms improved with previous treatment and which remained. Test results, diagnoses, and the course of previous treatment are important for understanding the current condition. Clinical research in modern Korean medicine, physiological and pathological research in modern medicine, and observations recorded in classical Korean medicine texts offer different perspectives on the same body. Rather than fitting a patient into one perspective, I consider what each can and cannot explain and look for clues that connect symptoms and treatment histories that were previously considered separately.

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